Dengue is the most rapidly expanding mosquito-borne virus with an increasing incidence and geographical area. The disease is most commonly found in the tropics, but there are occasional outbreaks in other places including Texas and Hawaii.
登革热是目前传播最快的由蚊子导致的病毒性疾病，它的发病率和流行区域都有增加的趋势。登革热在热带最常见，偶尔也可以在其它地区暴发，如德克萨斯和夏威夷。

Dengue has 3 phases. The febrile phase lasts 2-7 days and is similar to viral syndrome: high fever with nausea and vomiting. There may also be petechiae which can be induced by the application of a tourniquet. The critical phase occurs after defervescence and lasts only 24-48 hours. It is marked by increased capillary permeability and can lead to severe pulmonary edema, shock, and multisystem organ failure. The recovery phase is marked by hemodynamic improvement. Some patients have a rash described as “isles of white in a sea of red.” Some patients will develop bradycardia.
登革热有三期。发热期多持续2－7天，与普通病毒感染症状相似：伴有恶心和呕吐的高烧。可出现出血点，尤其在用止血带的地方。危重期在退烧后开始，可持续24－48小时。主要表现为由毛细血管通透性增加导致的严重肺水肿，休克，和多脏器功能衰竭。恢复期包括血液动力学的改善。有些病人会出现象‘红海中的白色岛屿’式的皮疹。

Most patients have a self-limited form of the illness that is not severe, and consists of symptoms seen in the febrile phase. The patients that develop severe dengue can have markers in the febrile phase that are associated with organ dysfunction, GI bleeding, and increased capillary permeability. Other concerning symptoms early are abdominal tenderness or persistent vomiting.
绝大多数只有发烧期症状的病人均可自愈，那些危重的病人将在发热期就会出现器官功能紊乱，消化道出血，和毛细血管通透性增加。其它早期的严重病例预兆包括腹部触痛和顽固性呕吐。

Treatment is supportive, mostly consisting of IV fluids, which is very effective when started early in the patient’s illness.
治疗是以支持和辅助为主，主要是静脉补液，在疾病的早期开始补液是一个非常有效的治疗措施。

For more information and maps of endemic areas check out the CDC or WHO websites:
需要了解能多的信息和流行区域的地理分布图，可参考CDC或WHO的网站：
http://wwwnc.cdc.gov/travel/notices/in-the-news/dengue-tropical-sub-tropical.htm
http://www.who.int/denguecontrol/en/

Resources 资料来源:
Dengue: guidelines for diagnosis, treatment, prevention and control – New Edition. (2009) World Health Organization.
Chen LH, Wilson ME. Dengue and chikungunya in travelers: recent updates. Curr Opin Infect Dis 2012 Oct;25(5):523-529.