Title: Prevention of Contrast-Induced Nephropathy
题目：阿托伐他汀（立普妥）与造影剂导致的肾病的预防
Author作者: FerminBarrueto

There have been many attempts to reduce the incidence of contrast-induced nephropathy.
减少造影剂导致的肾病的发生有很多的措施。
Mechanism usually centers around antioxidant properties or free radical scavengers that prevent the acute kidney injury that may result after intravenous contrast.
治疗的机制都是基于为防止静脉造影剂造成的急性肾损伤而使用抗氧化剂及游离基清除剂。
IV Fluid hydration, sodium bicarbonate and acetylcysteine have been studied with only some evidence.
静脉输液，碳酸氢钠和乙酰半胱氨酸已被临床应用，虽然还没有足够的证据。
There is also some controversial data that is beginning to surface regarding the use of atorvastatin with a recent article in Circulation 2012 that showed high dose atorvastatin (80mg) 24 hrs prior to angiography prevented contrast-induced acute kidney injury in patients with mild to medium risk.
最近有一些资料开始报道阿托伐他汀（立普妥）的作用。在2012年循环杂志中有一篇文章显示，血管造影前24小时给予高剂量（89mg）的阿托伐他汀（立普妥），可以防止具有轻中度危险病人的由造影剂导致的急性肾损伤。
Link to article has been provided:
原始文章可见这个网页：
http://circ.ahajournals.org/content/126/25/3008