Title: What to tell patients who are eligible to receive tPA
题目：要告诉适合tPA病人什么？
Author 作者: Michael Abraham, Bryan Hayes, and Sarah Dubbs

Remember that risk of intracranial hemorrhage is higher as severity of stroke goes up
要记住，颅内出血的危险随脑梗塞的严重程度而增加
Relatively young, healthy patients – smaller chance of intracranial hemorrhage ~4%
相对年轻和健康的病人－颅内出血的危险小，大约在4％
Older patients with comorbidities – increased chance of intracranial hemorrhage ~20%
年龄大并有并发症的病人－颅内出血的危险大，大约在20％
More difficult to assess overall benefit of tPA
很难评价tPA的准确效益
Improvement of function is a long process
功能的恢复需要很长时间
Best to inform them function is not guaranteed nor is it necessarily to baseline but it is more likely with tPA
最好要告诉病人，不能保证有功能的恢复或恢复到病前，但tPA的应用可增加功能恢复的可能性
Ultimately, the decision is up to the patient so inform them adequately
最终的决定还是要由病人来定，因此我们一定要提供充分的信息
Angioedema 血管性水肿
An adverse reaction to tPA that is common but often not mentioned
tPA的一个副反应，但经常被忽视
Occurs in 2-5% of patients receiving tPA
在接受tPA的病人中的发生率为2.5％
Usually not reversible
通常是不可逆的
Be prepared to intubate early should it occur
如出现血管性水肿，要准备做早期气管插管
Worth mentioning as a risk when doing consent for tPA
在考虑tPA时，值得提一下（血管性血肿）的危险