Title: Is that rash a mess? Maybe it’s DRESS.
题目：那个皮疹是一个困惑吧？要警惕DRESS
Author 作者: Haney Mallemat

DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) or DIHS (Drug-Induced Hypersensitivity Syndrome) is a potentially life-threatening adverse drug-reaction.
DRESS（伴有嗜酸性粒细胞增多和全身症状的药物不良反应）或DIHS（药物超敏反应综合症）是一个潜在的具有生命危险的药物反应。
Incidence is 1/1,000 to 1/10,00 drug exposures. It occurs 2-6 weeks after the drug is first introduced, distinguishing it from other adverse drug-reactions which typically occur sooner.
发生率为每1000到10000药物接触中有一例。有别于其它药物不良反应（常很快出现），DRESS一般在首次药物接触后2－6周出现，
The syndrome classically includes:典型的综合症表现包括：
Severe skin eruptions (typically morbilliform or erythrodermic eruptions)
严重的皮疹（典型麻疹样或红皮病）
Hematologic abnormalities (eosinophilia or atypical lymphocytosis)
血液学异常（嗜酸性粒细胞增多或非特异性淋巴细胞增多症）
Organ involvement; e.g., hepatic (most common), pneumonitis, renal failure, etc.
器官损伤：肝脏（最常见），肺炎，肾衰等）
Fevers 发烧
Arthralgia 关节痛
Lymphadenopathy 淋巴结肿大

The most commonly implicated drugs are anticonvulsants (e.g., carbamazepine, phenobarbital, and phenytoin), sulfonamides, and allopurinol. 
最常见的药物有：抗癫痫药（卡马西平，苯巴比妥，苯妥英钠），磺胺类，和别嘌醇。
Recovery is typically complete after discontinuing the offending drug; systemic steroids may promote resolution of the illness.
在停药后会完全恢复；全身用激素对疾病的恢复有帮助。

References 参考文献
Cacoub P. et al. The DRESS syndrome: a literature review. Am J Med 2011 Jul;124(7):588-597.