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Title: Varicella-related stroke
题目:与水痘有关的脑卒中
Author 作者: Jennifer Guyther
Acute ischemic stroke occurs in 3.3/100,000 children per year. Up to 30% of these are caused by varicella. This can be diagnosed if the patient has had varicella infection within the past 12 months, has a unilateral stenosis of a great vessel, and has a positive PCR or IgG from the CSF.
每年100,000名 中会有3.3儿童患急性缺血性脑卒中,其中高达30%是由水痘引起的。如有下列情况可以确诊,如果病人在过去12个月内有过水痘感染,具有单侧的一个大血管狭窄,并具有阳性PCR或脑脊液中IgG。
Treatment includes anticoagulation, acyclovir for at least 7 days and steroids for 3-5 days.
治疗包括抗凝,至少7天的无环鸟苷和3-5天的类固醇。
Outcome is normally good and spontaneous improvement can be seen.
预后一般来说是不错的,自然好转也是常见的。
Inflammation of other arteries, including other areas of the brain, can also be seen. Treatment options for this can include high dose glucocorticoids and possibly immunosuppresive agents.
其他动脉, 包括在其他的大脑区域也可以发生炎症。治疗方案可以包括高剂量的糖皮质激素和免疫抑制剂。
References 参考文献:
Simma et al. Therapy in pediatric stroke. Eur J Pediatr. Published online 06 November 2012.