Title: CVP and Fluid Responsiveness
题目：CVP与液体复苏反应
Author 作者: Michael Winters

Central venous pressure (CVP) has been used over the last 50 years to assess volume status and fluid responsiveness in critically ill patients.
中心静脉压（CVP）在过去50年已被用于评估危重病人的容量状态和对液体复苏的反应。
Despite widespread practice habit, CVP has not been shown to reliably predict fluid responsiveness in the critically ill.
尽管其普遍的应用，CVP还没有被证实能够可靠地预测危重病人对液体复苏的反应。
In a recent updated meta-analysis, Marik et al reviewed 43 studies, totaling over 1800 patients.
在最近的一个更新过的荟萃分析中，Marik等对43个研究进行了总结，总病人数超过了1，800例。
57% of patients were fluid responders
57％的患者液体复苏有反应
The mean CVP was 8.2 mm Hg for fluid responders and 9.5 mm Hg for non-responders
对液体复苏有反应的病人的平均CVP为8.2毫米汞柱，而无反应病人为9.5毫米汞柱
For studies performed in ICU patients, the correlation coefficient for CVP and change in cardiac index was just 0.28.
对于ICU患者进行的研究中，CVP与心脏指数变化的相关系数仅为0.28。

Bottom line: Current literature does not support the use of CVP as a reliable marker of fluid responsiveness.
要点：目前的文献不支持CVP作为一个可靠的液体反应指标。

References 参考文献：
Marik PE, Cavallazzi R. Does the central venous pressure predict fluid responsiveness? An updated meta-analysis and a plea for some common sense. Crit Care Med 2013:41:1774-1781.