Title: Drug-Induced Seizures in Children and Adolescents
题目：在儿童和青少年中药物引起的癫痫发作
Author作者: Bryan Hayes

Seizures can be the presenting manifestation of acute poisoning in children.
儿童急性中毒可以表现为癫痫发作。
A 3-year data set from the Toxicology Investigators Consortium (ToxIC) Case Registry identified 142 cases of drug-induced seizures in children < 18 years old. 75% were teenagers.
毒理学研究者协会（ToxIC）案例注册表中为期3年的数据显示有142例<18岁儿童因药物中毒而出现癫痫发作，其中75％是青少年。
Antidepressants were most commonly associated with causing seizures, especially bupropion and citalopram. Diphenhydramine was also a commonly identified cause.
最常见的与癫痫发作有关的是抗抑郁药，尤其是安非他酮和西酞普兰。苯海拉明也是一个常见的原因。
The authors conclude that clinicians managing teenagers presenting with seizures should have a high index of suspicion for intentional ingestion of antidepressants.
作者认为，临床医生在处理青少年癫痫发作时应该高度警惕有意的抗抑郁药中毒。
References参考文献
Finkelstein Y, et al. Drug-induced seizures in children and adolescsents presenting for emergency care: current and emerging trends. ClinToxicol 2013;51(8):761-6. [PMID 23957582]