Title: Tranexamic Acid in Anterior Epistaxis
题目：凝血酸在鼻前腔出血中的应用
Author 作者: Ellen Lemkin

Tranexamic Acid (TXA) topically applied was compared to anterior nasal packing in 216 patients with acute anterior epistaxis. Cotton pledgets (15 cm) soaked in injectable TXA (500 mg/5 ml) were inserted into the bleeding nostril and removed after bleeding had arrested. This was compared to standard anterior packing.

在216例急性鼻前腔出血病人中，对对氨甲基环己甲酸（凝血酸，TXA）局部应用与鼻前腔填塞进行了比较。将浸泡过注射用TXA（500毫克/5毫升）棉拭子（15厘米）插入出血的鼻孔，在出血停止后取出。这个方法与标准的鼻前腔填塞进行了比较。

RESULTS结果：

TXA凝血酸 Anterior packing鼻前腔填塞

% pts bleeding stopped in 10 min
10分钟内出血停止的比例（％） 71% 31.2%
Discharge after 2 hours
2小时后出院 95.3% 6.4%
Rebleeding in 24 h hours
24小时后再出血 4.7% 11%
Satisfaction scores
病人满意度（最好10分） 8.5 4.4

Bottom line: topical tranexamic acid looks promising for control of uncomplicated anterior epistaxis.

要点：

凝血酸在控制单纯鼻前庭出血时是有效的。

References参考文献：

Zahed R, Moharamzadeh P, AlizadeArasi S, Ghasemi A, Saeedi M. A new and rapid method for epistaxis treatment using injectable form of tranexamic acid topically: a randomized controlled trial. AJEM 2013 (31):1389-1392.
http://www.ncbi.nlm.nih.gov/pubmed/23911102