Title: Cardiovascular Morbidity & Sleep Apnea
题目：心血管疾病发病率与睡眠呼吸暂停
Author 作者: Semhar Tewelde
翻译：郑辛甜 校对：肖锋

Obstructive sleep apnea (OSA) is characterized by sleep-related periodic breathing, upper-airway obstruction, sleep disruption, and hemodynamic perturbations.
阻塞性睡眠呼吸暂停（OSA）的特点为睡眠中周期性呼吸、上呼吸道阻塞、睡眠中断以及血流动力学紊乱。
Epidemiological data shows a strong association between untreated OSA & cardiovascular morbidity/mortality.
流行病学资料显示未治疗的OSA和心血管疾病的发病率/病死率有明显的相关性。

Two recent studies by Gottlieb et al. (1) & Chirinos et al. (2) elucidated two important explicit and complicit treatment considerations for OSA:
近期的两项研究提出了两种重要的有效且有协同作用的OSA治疗方案。

(1) In moderate-to-severe obstructive sleep apnea, the use of CPAP alone during sleep may ameliorate systemic hypertension and cardiovascular risk, even in patients who do not have "subjective" sleepiness.
（1）对中度-严重的OSA，睡眠中单独使用持续正压通气（CPAP）或可改善全身性高血压和心血管疾病风险，甚至对那些没有“主观症状的”嗜睡患者也是如此。

(2) Weight loss combined with CPAP use may further decrease cardiovascular morbidity .
（2）减重结合使用CPAP可进一步减少心血管疾病风险。

References 参考文献：
Basner R. Cardiovascular Morbidity and Obstructive Sleep Apnea. N Engl J Med 2014; 370:2339-2341 June 12, 2014