Title: IV Magnesium for Acute Migraine Headache
题目：静脉镁治疗急性偏头痛
Author 作者: Bryan Hayes
翻译：葛赟 校对：肖锋

Does IV magnesium have a role in the management of acute migraine headache in the ED? A new study says yes. [1]
静脉镁对治疗急性偏头痛有作用吗？一项新的研究说有作用的[1].

Intervention 干预：
1 35 patients received IV magnesium 1 gm over 15 minutes.
35例患者接受超过1g 镁静脉注射15分钟。
2 35 patients received IV dexamethasone 8 mg + IV metoclopramide 10 mg over 15 minutes.
35例患者接受8mg 地塞米松和10mg甲氧氯普胺静脉注射15分钟
3 Each group contained men and women.
每组患者都有男性和女性

What They Found
他们的结果是什么
Magnesium sulfate was more effective in decreasing pain severity at 20-min and 1- and 2-h intervals after treatment (p < 0.0001) compared to treatment with dexamethasone/metoclopramide.
与注射地塞米松和甲氧氯普胺治疗急性偏头痛相比较，静脉硫酸镁在注射后20分钟时，1小时，和2小时，明显减轻疼痛程度（P<0.0001）

Application to Clinical Practice
在临床实践中的应用


Two previous studies found mixed results using magnesium. [2, 3] This new study found that IV magnesium may be an additional option, even compared to a common treatment regimen... yet another possible use for magnesium in the ED.
之前两篇使用镁的文章，结果模糊不清[2][3]。这篇新研究发现，与常见的治疗方案比，静脉镁可能是治疗急性偏头痛的另外一个选择，很可能会是镁在急诊科的另一个用途。

References 参考文献：
1. Shahrami A, et al. Comparison of therapeutic effects of magnesium sulfate vs. dexamethasone/metoclopramide on alleviating acute migraine headache. J Emerg Med 2015;48(1):69-76. [PMID 25278139]
2. Corbo J, et al. Randomized clinical trial of intravenous magnesium sulfate as an adjunctive medication for emergency department treatment of migraine headache. Ann Emerg Med 2001;38(6):621-7. [PMID 11719739]
3. Cete Y, et al. A randomized prospective placebo-controlled study of intravenous magnesium sulphate vs. metoclopramide in the management of acute migraine attacks in the Emergency Department. Cephalagia 2005;25(3):199-204. [PMID 15689195]